Nerolidol

Nerolidol is isomer-specific

Nerolidol is a sesquiterpene alcohol. Papers may distinguish trans or E-nerolidol from cis or Z-nerolidol, so the exact form matters when a laboratory result is compared with research. The name alone does not identify a product or a medical result.

The evidence used human cells outside the body

Researchers analysed essential oils from poplar buds and propolis, then tested pure nerolidol on human neutrophils ex vivo. Nerolidol altered calcium influx and reduced activation responses to two laboratory agonists. This is human-cell evidence obtained outside a living person. It is not a clinical study of medical cannabis.

Label language should keep the isomer visible

If a report lists nerolidol, E-nerolidol or another form, record which name the assay gives and whether the result is qualitative or quantitative. A label entry does not show that the same concentration, mixture or biological setting used in the neutrophil experiment exists in a prescribed product. The MCPH terpene reference is useful for comparing the names.

The cited work supports a laboratory question about neutrophil activation. It does not establish a human clinical benefit, an anti-inflammatory treatment effect or a product response.

Related conditions

• Anxiety disorders
• Sleep disorders

Sources

• Neutrophil immunomodulatory activity of nerolidol (primary human-cell/laboratory study, PMID 36501438, DOI 10.3390/plants11233399).