Glossary term

Drug-drug interaction: A drug-drug interaction happens when one medicine changes the effect, level or safety profile of another.

EssentialClinical / safetySource quality: HighLast updated: 29 June 2026

Why this term matters

Critical for patients taking epilepsy medicines, sedatives, hormonal contraception or other centrally acting drugs.

UK medical cannabis context

NICE tells prescribers to consider interactions, including with CNS depressants, antiepileptics and hormonal contraceptives; NHS also warns CBD and THC can affect other medicines.

What not to assume

Interactions can increase side effects, alter liver metabolism or change efficacy.

Careful wording: Avoid implying interaction checking is optional.

Related glossary terms

Related MCPH pages

Sources and review notes

This entry is educational vocabulary, not medical advice. Suitability, prescribing, product choice and monitoring belong with a qualified clinician or pharmacist.