Patient guide

B28 Cannabis Strain Review

The B28 cannabis strain is a sativa-dominant hybrid resulting from the crossbreeding of Skunk #1 and Green Crack. It is often marketed for its potency and distinct flavour profile. However, for patients and carers...

13 June 2026 3 min read min read

The B28 cannabis strain is a sativa-dominant hybrid resulting from the crossbreeding of Skunk #1 and Green Crack. It is often marketed for its potency and distinct flavour profile. However, for patients and carers seeking to understand its potential benefits and risks, it is important to approach the information with a critical and evidence-based perspective. This guide provides an overview of the available information on B28, including its characteristics, the evidence supporting its use, and considerations for patients and clinicians.

Key takeaways

  • B28 is a sativa-dominant hybrid strain, derived from Skunk #1 and Green Crack, and is often associated with high THC content.
  • The strain is marketed for its potency and flavour, but there is limited scientific evidence to support specific therapeutic benefits.
  • Patients should be aware that cannabis products, including B28, can vary significantly in potency and composition between batches.
  • The effects of B28 can vary depending on the method of consumption, individual tolerance, and the presence of other cannabinoids or terpenes.

Evidence base

The available evidence on B28 is primarily based on anecdotal reports and commercial marketing rather than rigorous scientific studies. As a hybrid strain, B28 is often described as having a strong, pungent aroma and a sweet, spicy taste. These sensory characteristics are commonly cited in product descriptions, but they do not necessarily translate to therapeutic efficacy.

While some users report that B28 may help with conditions such as chronic pain, anxiety, or insomnia, these claims are not supported by clinical trials. The lack of standardised testing and regulation of cannabis products means that the actual potency and composition of B28 can vary significantly between different sources. This variability makes it difficult to predict the effects or safety profile of the strain.

In the UK, the Medicines and Healthcare products Regulatory Agency (MHRA) regulates cannabis products that are licensed for medicinal use. However, B28 is not currently licensed for any medical condition in the UK. This means that any use of B28 for therapeutic purposes is outside the scope of licensed medical cannabis and may not be covered by the NHS. Patients should be cautious about relying on unverified claims about the strain’s benefits.

The absence of robust clinical data on B28 means that its potential therapeutic applications remain speculative. While some individuals may find relief from symptoms using this strain, it is important to consider that cannabis can have side effects, including cognitive impairment, dependency, and interactions with other medications. Therefore, any use of B28 should be approached with careful consideration of the risks and benefits.

What patients should know

B28 is a cannabis strain that is often associated with high THC content and a strong, distinctive flavour. However, it is important to understand that the effects of cannabis can vary widely between individuals and between product batches. This variability is due to differences in cultivation, processing, and the presence of other compounds such as CBD and terpenes.

Patients should also be aware that the legal status of cannabis in the UK is complex. While cannabis is classified as a controlled substance, it is available for medical use under specific licences. B28 is not currently licensed for medical use in the UK, so its use for therapeutic purposes is not supported by the NHS or regulated by the MHRA. This means that patients should not rely on B28 as a substitute for licensed medical treatments.

Another important consideration is the potential for adverse effects. Cannabis can cause a range of side effects, including dizziness, dry mouth, and changes in mood or cognition. These effects can be more pronounced in individuals who are new to cannabis or who consume high-potency products. Patients should be cautious about using B28, especially if they have a history of mental health issues or are taking other medications.

When to speak to a clinician

Patients should consider speaking to a clinician if they are experiencing adverse effects from using B28, if they are unsure about the safety or effectiveness of the strain, or if they are considering using cannabis for a medical condition. It is also important to consult a clinician if the patient is taking other medications, as cannabis can interact with certain drugs.

Red flags that may indicate the need for professional advice include persistent or severe side effects, changes in mental health or behaviour, or difficulty managing symptoms despite use of the strain. Patients should also seek medical advice if they are concerned about the legal or regulatory status of cannabis use in the UK, or if they are unsure about the appropriate dosage or method of consumption.

Questions to ask a clinician

  • What are the potential risks and benefits of using B28 for my specific condition?
  • How might B28 interact with other medications I am currently taking?
  • Are there alternative cannabis products or treatments that may be more suitable for my needs?

Source trail

  • MHRA guidance on the regulation of cannabis products in the UK
  • Information on the legal status of cannabis in the UK from the Home Office
  • Commercial product descriptions and user reviews for B28 cannabis strain